As complex care gains momentum, organizations and providers are finding innovative ways to serve individuals’ complex health and social needs. However, transforming the way care is delivered requires policy change and new payment models. In this blog post for JAMA Forum, Lauran Hardin, our Senior Advisor for Partnerships and Technical Assistance, and Diana Mason, of George Washington University’s School of Nursing, write about two new Centers for Medicare and Medicaid Services opportunities that incentivize innovative complex care models. First, the Emergency Triage, Treat and Transport (ET3) initiative, is expanding opportunities for ambulance care teams to bring patients to primary or urgent care, or connect patients with telemedicine providers. Second, Primary Care First creates five new payment models that encourage primary care providers to keep their patients healthy, stable, and at home.